Did you try these https://www.amd.com/en/support/chipsets/amd-socket-am4/b350 ?

Can you please try and run a live Ubuntu (or any other Linux) USB and see if you'll get stuttering again? Running a different OS aims to test a different set of drivers. As your USB devices don't have issues w/o the hub, it's most likely the hub or some bad driver.

It's always a good idea to ask here:

https://support.amd.com/en-us/contact/email-form

https://www.asrock.com/support/index.asp?cat=RMA

and of course your USB hub provider

But I'm noticing that the Chipset drivers do not include windows 10 USB drivers for some reason.  So the drivers I'm using are all from Microsoft and seem out of date despite repeated attempts to update them.

Windows 7 drivers are included, but windows 10 does recognize them as matching.

I tried it, Situation seems improved as I haven't notice any skipping in 20 minutes. It was happening about every minute before.

But the device recognition is still off.

https://www.dropbox.com/s/ekvy6nn1x1xfbqq/Screenshot%202018-09-26%2001.47.10.png?dl=0

https://www.dropbox.com/s/g06x93rea3h44rs/Screenshot%202018-09-26%2001.47.23.png?dl=0

https://www.dropbox.com/s/0xtnhublwbrp5p6/Screenshot%202018-09-26%2001.47.31.png?dl=0

The wireless transceiver should only show Microsoft Keyboard(maybe mouse too if it's a unifying)

Do you think it's all right to use AMD's chipset drivers instead of ASRock's?

The reason I ask is that if you look at the BIOS download page for your board you will see that 5.00 lists "Enhance USB Compatibility":

https://www.asrock.com/mb/AMD/AB350%20Pro4/#BIOS

If you do opt to update the BIOS make sure to use the Instant Flash method. Restore factory defaults in your UEFI and restart the system before you update, this will help remove some of the risk often involved with BIOS updates.

Good luck.

I am currently using an extension cord for somethings, but that doesn't resolve the hub issue, some devices have hubs built in (like my card reader).

I don't see any USB Filter drivers installed,  does it go by any other name or is there a way to force installation?

Bad USB driver is a good guess. Even better one is missing chipset ones. Chipset drivers include a USB filter driver, which might be what is wrong with your system.

Try running the USB devices without a hub and see if the problem is still there.

On a side note - why use a hub? It only makes sense if you need a longer cords, but even then I'd pick a quality extension cable.

Most notably, Windows 10 will display the hub connected devices with the name of a device already plugged in from "Bluetooth and other devices" page and the eject safely menu.